Who was the first to divorce in desperate housewives?!
Question: Who cares?
It's not real!
Answers: Who cares?
It's not real!
Susan I think
Technically that would be Susan Mayer, as she started the show as a divorcee. Carlos and Gabriella are the only other ones to be divorced, as Bree was actually widowed. I don't think Edie was ever married.
During the course of the show, the only main couple to have divorced is Carlos and Gabriel. Before the events in the first episode, Susan has been divorced from her husband, Karl, and Edie has been divorced twice. Gabriel, I believe, is now going through her second divorce and Brie's first husband died at the end of the first season.